We are pleased that you are considering volunteering for clinical research. It is through clinical research that we advance medicine. Participation in a clinical research is completely voluntary.
Each study has specific requirements on who can participate, which may include age, gender, and medical diagnosis. Prior to enrolling in any study, a study team member will explain the study details to you.
Join The Contact Registry For Clinical Research
Sign up for the UCF College of Medicine’s Contact Registry for Clinical Trials to learn about clinical research and clinical trials in areas of interest to you. Whenever a study is opening in your interest area, we will let you know. You do not have to be a patient or have the disease, just need to be interested in learning more.
Join The Registry PAB Recruitment FlyerInformation on Volunteering for Research from the United States Department of Health & Human Services, Office of Human Research Protections
Trials Open For Enrollment
Study: Crowdsourcing an open breast cancer radiograph imaging repository for artificial intelligence research
PIs: Dr. Dexter Hadley, MD, PhD; Dr. Mariana Dangiolo, MD; Dr. Amoy Fraser, PhD, PMP, CCRP
We are seeking adults 18 years or older who has had any screening or diagnostic breast cancer imaging performed at a U.S. institution with either positive or negative results. You must also have an email address and access to reliable internet.

Study: Post-pandemic genomic epidemiology of pneumococcal carriage among children and adults in the general US population
PI Dr. Taj Azarian, Co-I Dr. Virgil Dawson, Dr. Amoy Fraser
We are seeking HEALTHY adults over 50 years old and children under 5 years old to participate. You don’t need to be ill with pneumonia to participate. The 30-minute study visit involves a questionnaire and a nasopharyngeal swab. As thanks, we are giving a $30 Amazon gift card. To participate, contact COMTrials@UCF.edu or 407 COM TRIALS.
We are seeking patients in all disease areas to serve as subject matter experts/advisors for our research studies. The only qualification is your lived, personal experience of the disease. The commitment is less than 20 hours a year. To volunteer to be an EXPERT, reach out to COMTrials@UCF.edu or 407 COM TRIALS.

Sign up for the UCF College of Medicine’s Contact Registry for Clinical Trials to learn about clinical research and clinical trials in areas of interest to you!
Study: Contact Registry for Clinical Trials
Seeking: Any adult
PI: Dr. Amoy Fraser, PhD

Study: Development of an Early Diagnostic Test for Malignant Tumors in Children with NF1
Seeking: Healthy persons to donate blood
PI: Dr. Cristina Fernandez-Valle

Study: De-Identified Human Tissue Project for Use with Translational, Biomedical Research at UCF College of Medicine and Burnett School of Biomedical Sciences
Seeking: Persons who will be doing a surgery to donate removed tissue
PI: Dr. Amoy Fraser, PhD

Limited participants- Astronauts Only.
Collaborating PI: Dr. Amoy Fraser, PhD

Study: Extracellular vesicles as non-invasive biomarkers for Huntington Disease progression and huntingtin lowering therapy
Seeking: (1) Persons with HD; and (2) Healthy persons without HD to serve as controls
PI: Dr. Amber Southwell, PhD; Dr. Danish Bhatti, MD

Study: Innate Immunity in Allergic Asthma
Seeking: Healthy persons (no asthma, no respiratory symptoms, no seasonal allergies) to donate blood
PI: Dr. Justine Tigno-Aranjuez, PhD

Study: Translational Utility of Tumor-Derived FGF19 in a Novel Blood-Based Endocrine Suppression Approach for Colorectal Cancer Screening
Seeking breast cancer and colorectal cancer patients.
PI Dr. Deborah Altomare, MD; Dr. Virgil Dawson, MD.

Study: Blood Collection for COM and BSBS Scientists.
Seeking: adult blood donors.
PI Amoy Fraser, PhD.

Study: Lake Nona Life Project.
Seeking: Persons who live, work, study, or play in Lake Nona.
Sign up at http://www.liveworkparticipate.com/
PI Eric Schrimshaw, PhD.

FINE REAL: A non-interventional study providing insights into the use of Finerenone in a routine clinical setting.
Seeking adults who are taking Kerendia (Finerenone).
PI Virgil Dawson, MD.

Trials Opening Soon For Enrollment
Study: The Effect of Music Therapy on Neurochemical Biomarkers in Patients with Alzheimer’s Disease
We are seeking patients that are 50 years or older to participate in a study evaluating the effects of music therapy on Alzheimer’s disease. Procedures include providing a saliva sample before and after a complementary live string quartet. To participate, contact COMTrials@UCF.edu or 407 COM TRIALS.
PIs: Dr. Kiminobu Sugaya; Dr. Ayako Yonetani; Dr. Amoy Fraser, PhD


PI: Dr. Thomas Kean, PhD

Study: Hair Analysis for Dialysis Patients. Open to dialysis patients
Seeking Veterans doing dialysis at the Orlando VA.
PI Ed Ross, MD.

Trials Closed For Enrollment
Study: A Biospecimen Samples Collection Study to Support the Development of the Detect STI Test
Seeking: *Limited Access* UCF Students Only
PI: Dr, Jane Gibson, PhD; Dr. Mary Schmidt-Owens, PhD

Study: Deciding Brains
This study is looking at changes in memory for older adults.
Seeking: Persons ages 60-95 with memory issues but no dementia
PI: Dr. Nichole Lighthall, PhD; Dr. Mariana Dangiolo, MD

*LIMITED ACCESS* Medical Students only

Study: Cell-Free DNA CHIP for Diagnosing Cancer
Seeking: Healthy persons & persons with cancer to donate blood
PI: Dr. Kersten Schroeder

Study: Cobas® Liat SARS-CoV-2, Influenza A/B & RSV Nucleic Acid Test: Clinical Performance Evaluation
Seeking: *Limited Access* UCF Students Only
PI: Dr. Jane Gibson, PhD; Dr. Mary Schmidt-Owens, PhD

Study: Targeting Immunometabolism to control COVID19
Seeking: Healthy persons to donate blood
PI: Dr. Hung Nguyen, PhD

Study: Rheumatology Fellows’ Survey: Opinion on the Influence of Artificial Intelligence and Social Media
Seeking: Rheumatology students
PI: Dr. Neha Bhanusali, M.D.

Collection of human blood for development of liquid biopsy assay
Seeking: Healthy persons to donate blood
PI: Dr. Annette Khaled, PhD

Study: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Adaptive, Phase III trial to Investigate Efficacy and Safety of Vilobelimab in the Treatment of Ulcerative Pyoderma Gangrenosum (IRX1001/IFX-1-P3-4)
This study seeks persons with ulcerative pyoderma gangrenosum to find out if a new investigational drug, vilobelimab is safe and effective in treating the condition.
Seeking: Persons diagnosed with Ulcerative Pyoderma Gangrenosum.
PI. Dr. Naveed Sami, MD

Study: A Randomized, Controlled Pragmatic Phase 3b/4 Study of Baricitinib in Rheumatoid Arthritis
Seeking: Persons diagnosed in Rheumatoid Arthritis
PI: Dr. Shazia Beg, MD

Study: A Prospective Observational Study of Patients receiving Dupixent for Prurigo Nodularis
Seeking: persons diagnosed with Prurigo Nodularis
PI: Dr. Naveed Sami, MD
Study: A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of Deucravacitinib (BMS-986165) in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
Seeking: Persons diagnosed with Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
PI: Dr. Naveed Sami, MD

Study: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid
Seeking adults with BP that is not adequately controlled
PI Naveed Sami

Study: Sarcopenic Obesity in the Elderly.
Seeking adults over age 60.
PIs Muthu Periasamy, PhD; Ali Rizvi, MD; and Mariana Dangiolo, MD.

Study: Microbiome in aging Gut and Brain (MiaGB) Study.
Seeking: Persons over 60 years old.
LSI Michal Masternak, PhD.

Study: The Eye in Orbit: UCF Adaptation.
Seeking: Selective enrollment. Not open to the public.
LSI Mehul Patel, MD.

Study: Crowdsourcing an Open COVID-19 Chest Radiograph Imaging Repository for Artificial Intelligence Research.
Seeking: persons who had a chest Xray while diagnosed with COVID19.
PI: Dexter Hadley.

A Randomized, Double-Blinded, Placebo-Controlled Trial to Investigate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 SC in Adult Patients with Pemphigus (Vulgaris or Foliaceus)
PI Naveed Sami, MD.
