The mission of the Immunity and Pathogenesis Division is elucidation of the cellular and molecular mechanisms at the interface of infection, inflammation and immunity. Our group has broad interest and expertise in microbial pathogenesis, innate immunity, inflammatory signaling pathways and immunological memory. Our discoveries are being translated into innovative diagnostics, vaccines, and therapeutic strategies to improve human health.
 
We have projects related to respiratory diseases (Influenza, Parainfluenza, Respiratory Syncytial Virus, Asthma and Tuberculosis), sexually transmitted diseases (Chlamydia trachomatis, Human papilloma virus and Zika virus), vector-borne diseases (Lyme disease and emerging vector borne viruses) and inflammatory diseases (Inflammatory bowel disease).
 
Our research division is structured as a collaborative, community environment that allows frequent interactions between students, postdocs and faculty.
 

Immunity and Pathogenesis Division Faculty

    Dr. Griff Parks
  • Title: Interim Associate Dean of Research; Director, Burnett School of Biomedical Sciences and Professor
  • Office: BBS 101G
  • Phone: 407.266.7011
  • Investigating innate immune responses to RNA viruses, including parainfluenza virus, bunyavirus and Zika virus & development of novel virus vectors as vaccines and anti-cancer therapies
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    Dr. Mollie W. Jewett
  • Title: Associate Professor, Immunity and Pathogenesis Division Leader
  • Office: BBS 218
  • Phone: 407.266.7028
  • Our lab focuses on molecular mechanisms of gene regulation and pathogenesis of the Lyme disease spirochete, Borrelia burgdorferi & Lyme disease diagnostics
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    Dr. Travis Jewett
  • Title: Associate Professor
  • Office: BBS 221
  • Phone: 407.266.7029
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    Dr. Kai McKinstry
  • Title: Assistant Professor
  • Office: BBS 449
  • Phone: 407.266.7137
  • Strategies to generate protective memory T cell populations & T cell-mediated protection against influenza virus
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    Dr. Kyle Rohde
  • Title: Assistant Professor
  • Office: BBS 238
  • Phone: 407.266.7124
  • Studies (i) Pathogenesis and gene regulation in Mycobacterium tuberculosis and M. abscessus (ii) Antibiotic drug discovery targeting Mycobacteria (iii)Mechanisms of drug resistance in pathogenic Mycobacteria (iv) Diagnostic tools for detection of drug resistant TB
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    Dr. Tara Strutt
  • Title: Assistant Professor
  • Office: BBS 442
  • Phone: 407.266.7144
  • Memory CD4 T cell regulation of inflammatory responses & Protective roles of innate lymphoid cells during respiratory virus infection
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    Dr. Justine Tigno-Aranjuez
  • Title: Assistant Professor
  • Office: BBS 338
  • Phone: 407.266.7142
  • Post-translational modifications occurring in innate immune signaling pathways involved in inflammatory disease with a particular focus on NOD2 signaling & Molecular mechanisms underlying the pathogenesis of inflammatory bowel disease (IBD) and allergic asthma
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Immunity and Pathogenesis Affiliate Faculty

Kenneth Alexander, M.D., Ph.D., Nemours Children’s Hospital

Nyla Dil, D.V.M.,  Ph.D., COM Medical Education

Le-Chu Su, M.D., Ph.D., COM Internal Medicine

Bradley Willenberg, Ph.D., COM Internal Medicine