Most M.D. Programs that the LCME accredits use AMCAS as the initial application to the M.D. Program. AMCAS provides applicants with a single-source application for all participating M.D. Programs. The AMCAS application is usually available in May for completion and submission by the end of that calendar year. The AMCAS application must be submitted in the calendar year before the year that an applicant desires to attend an M.D. Program. For example, an applicant that wants to begin medical school in July 2023 may start their AMCAS application as early as May 2022. AMCAS Applications must be submitted by November 15, 2022, at the very latest, for a Fall 2023 enrollment.