Most M.D. Programs which are accredited by the LCME use AMCAS as the initial application to the M.D. Program. AMCAS provides applicants with a single-source application for all participating M.D. Programs. The AMCAS application is usually available in May each year for completion and submission by the end of that calendar year. The AMCAS application must be submitted in the calendar year prior to the year that an applicant desires to attend an M.D. Program. For example, an applicant that desires to begin medical school in July 2022 may begin their AMCAS application as early as May 2021. AMCAS Applications must be submitted by November 15, 2021, at the very latest for a Fall 2022 enrollment.