R. Lane Coffee, Jr., PhD, MS, is an Assistant Professor of Medicine at the University of Central Florida College of Medicine. Dr. Coffee was recruited to advance and support clinical and translational research at the College of Medicine and among its partner institutions, including the VA Medical Center, Nemours Children’s Health, and UCF Health and HCA Florida affiliates. As a nationally recognized leader in collaborative and team science, particularly in collaboration with the NIH, Dr. Coffee will work with faculty, residents, and medical and doctoral students to increase College of Medicine extramural funding, presentations, publications, and recognition as leaders in advancing patient care. Dr. Coffee also teaches grant writing skills to all members of the medical community and has previously won several teaching awards for his work with students.

Prior to joining UCF, Dr. Coffee was an Assistant Professor of Clinical Emergency Medicine, Research Navigator, and Program Manager of the Project Development Teams (PDTs) and Science Communication Studio at Indiana University and the Indiana Clinical and Translational Sciences Institute (CTSI). Coffee served as a resource for trainee- and faculty-related research endeavors including project/study development as well as protocol and grant development and writing. As navigator, he was a primary liaison for connecting investigators to scientific resources and services across the state and among CTSI partner institutions (Indiana University, Purdue University, University of Notre Dame). He was also responsible for managing research portfolios of investigators utilizing the PDTs as well as direct oversight and management of the Science Communication Studio which supports scientific communication skills development and advice using one-on-one meetings, peer review facilitation, and workshops to position investigators to be better equipped to communicate with the public and submit more effective grants and manuscripts.

With a background in neuroscience and chemistry, Coffee received a PhD in neuroscience (with a focus on Fragile X Syndrome) from Vanderbilt University, an MS in chemistry (studying aminoglycoside interactions with DNA and RNA triple helices) from Clemson University and completed post-doctoral training at both Northwestern University in Chicago and at the Fred Hutchinson Cancer Research Center in Seattle.

In his spare time, Dr. Coffee enjoys Orangetheory Fitness, traveling to sunny destinations, and exploring local restaurants.

Recent Publications:

Peer Reviewed:

  • Curtis, M; Kanis, J; Wagers, B; Coffee, Jr., RL; Sarmiento, E; Grout, S; Johnson, O; DiGregory, S; Grout, R. Immunization Status and the Management of Febrile Children in the Pediatric Emergency Department: What Are We Doing? Pediatr. Emer. Care. 2023. 39(1): 1-5. 
  • Brightman, AO; Coffee, Jr., RL; Garcia, K; Lottes, AE; Sors, TG; Moe, SM; Wodicka, GR. Advancing medical technology innovation and clinical translation via a model of industry-enabled technical and educational support: Indiana Clinical and Translational Sciences Institute’s Medical Technology Advance Program. J. Clin. Transl. Sci.  2021; 5(1): e79: 1-8. 
  • Coffee, Jr., RL; Williamson, AJ; Adkins, CM; Gray, MC; Page, TL; Broadie, K. In Vivo Neuronal Function of the Fragile X Mental Retardation Protein is Regulated by Phosphorylation, Hum. Mol. Genet. 2012; 21(4): 900-915.
  • Coffee, Jr., RL; Tessier, CR; Woodruff, III, EA; Broadie, K. Fragile X Mental Retardation Protein has a Unique, Evolutionarily Conserved Neuronal Function Not Shared with FXR1P or FXR2P, Dis. Model. Mech. 2010; 3(7-8): 471-485.
  • Adams, DG; Coffee, Jr., RL; Zhang, H; Pelech, S; Strack, S; Wadzinski, BE. Positive Regulation of Raf1 MEK1/2-ERK1/2 Signaling By Protein Serine/Threonine Phosphatase 2A Holoenzymes, J. Biol. Chem. 2005; 280(52): 42644-42654.
  • Arya, DP; Coffee, Jr., RL; Xue, L. From Triplex to B-form Duplex Stabilization: Reversal of Target Selectivity by Aminoglycoside Dimers. Bioorg. Med. Chem. Lett. 2004; 14(18): 4643-4646.
  • Arya, DP; Micovic, L; Charles, I; Coffee, Jr., RL; Willis, B; Xue, L. Neomycin Binding to Watson-Hoogsteen (W-H) DNA Triplex Groove: A Model. J. Am. Chem. Soc. 2003; 125(13): 3733-3744.

Book Chapters:
  • Coffee, Jr., RL; Sawning, S; Hobgood, C. Chapter 43: Female Resident. In: Martin, ML; Heron, S; Moreno-Walton, L; Strickland, M, eds. Diversity and Inclusion in Quality Patient Care: A Case-Based Compendium, Second Edition. Springer Nature, 2019.
  • Samra, HA; Coffee, Jr., RL; Cico, SJ. Chapter M20: Management of Former Preterm Infant. In: Sherman, SC; Cico, SJ; Nordquist, E; Ross, C; Wang, E., eds. Atlas of Clinical Emergency Medicine, 1st edition. Philadelphia: Wolters Kluwer, 2016.

For a full list of publications, visit:

Education & Specialties

  • MS, Chemistry, Clemson University, Clemson, SC
  • PhD, Neurobiology , Vanderbilt University, Nashville, TN
  • Post-Doctoral Fellowship, Vaccine and Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA
  • Post-Doctoral Fellowship, Neurobiology, Northwestern University, Evanston, IL
  • Neurobiology
  • Chemistry
Research Interests:
  • Project Development
  • Scientific Grant Writing
  • Clinical and Translational Research

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