Biomaterials and Nanomedicine
Our laboratory focuses on the expansive field of biomaterials and nanomedicine, where our research intersects tissue engineering, regenerative medicine, and therapeutics delivery systems. This includes the creation and analysis of novel bioabsorbable implants, scaffolds, and nanoparticles. Our laboratory has also been equipped to perform ultrasound therapy. We culture cell-material constructs and study the delivery kinetics of therapeutics from nanoparticles as a promising strategy for bone healing and osteoporosis treatment. Sound waves will be used to enhance tissue regeneration and control the delivery of therapeutics from nanocarriers. Equipped with these tools, we assess the angiogenesis, osteogenesis, immune response, and antibacterial efficacy of biomaterials and develop structures and compositions that promote the differentiation of stem cells to therapeutic cells. In addition, the laboratory has been equipped for cell and molecular biology, focusing on translational research for current clinical needs.
Ongoing work is centered around the following subjects:
Advanced Biomanufacturing
Engineering bioabsorbable magnesium implants by developing new material processing strategies and discovering process-structure-property relationships with particular emphasis on the role of structural refinement and its effect on biological properties
Bridging the Gap: Healing Injured Bones
Researching new ways to reconstruct bone injuries, including creating new magnesium-based scaffolds with mesenchymal stem cells by utilizing 3D-printing and laser micromachining techniques to replace the need for conventional bone grafts
Nanodelivery Systems and Devices
Synthesizing controlled release systems that can be ultrasonically triggered to modulate gene release from nanocarriers for osteoporosis treatment