MK Gupta. Therapeutic potential of epigenetic drugs. Epigenetics in Human Disease-Third Edition 2, 761-771. 2024, https://doi.org/10.1016/B978-0-443-21863-7.00005-6
Randhawa PK, Rajakumar A, Futuro de Lima IB, Gupta MK. Eugenol attenuates ischemia-mediated oxidative stress in cardiomyocytes via acetylation of histone at H3K27. Free Radic Biol Med. 2023 Jan;194:326-336. doi: 10.1016/j.freeradbiomed.2022.12.007. Epub 2022 Dec 13. PubMed PMID: 36526244; PubMed Central PMCID: PMC10074330.
Gupta MK, Randhawa PK, Masternak MM. Role of BAG5 in Protein Quality Control: Double-Edged Sword?. Front Aging. 2022;3:844168. doi: 10.3389/fragi.2022.844168. eCollection 2022. Review. PubMed PMID: 35821856; PubMed Central PMCID: PMC9261338.
Rabbani MY, Rappaport J, Gupta MK. Activation of Immune System May Cause Pathophysiological Changes in the Myocardium of SARS-CoV-2 Infected Monkey Model. Cells. 2022 Feb 10;11(4). doi: 10.3390/cells11040611. PubMed PMID: 35203260; PubMed Central PMCID: PMC8869860.
Kashyap S, Rabbani M, de Lima I, Kondrachuk O, Patel R, Shafiei MS, Mukker A, Rajakumar A, Gupta MK. HOPX Plays a Critical Role in Antiretroviral Drugs Induced Epigenetic Modification and Cardiac Hypertrophy. Cells. 2021 Dec 8;10(12). doi: 10.3390/cells10123458. PubMed PMID: 34943964; PubMed Central PMCID: PMC8700328.
Kashyap S, Mukker A, Gupta D, Datta PK, Rappaport J, Jacobson JM, Ebert SN, Gupta MK. Antiretroviral Drugs Regulate Epigenetic Modification of Cardiac Cells Through Modulation of H3K9 and H3K27 Acetylation. Front Cardiovasc Med. 2021;8:634774. doi: 10.3389/fcvm.2021.634774. eCollection 2021. PubMed PMID: 33898535; PubMed Central PMCID: PMC8062764.
Randhawa PK, Scanlon K, Rappaport J, Gupta MK. Modulation of Autophagy by SARS-CoV-2: A Potential Threat for Cardiovascular System. Front Physiol. 2020;11:611275. doi: 10.3389/fphys.2020.611275. eCollection 2020. Review. PubMed PMID: 33329064; PubMed Central PMCID: PMC7734100.
Randhawa PK, Gupta MK. Melatonin as a protective agent in cardiac ischemia-reperfusion injury: Vision/Illusion?. Eur J Pharmacol. 2020 Oct 15;885:173506. doi: 10.1016/j.ejphar.2020.173506. Epub 2020 Aug 26. Review. PubMed PMID: 32858050; PubMed Central PMCID: PMC8025154.
Cheung JY, Gordon J, Wang J, Song J, Zhang XQ, Prado FJ, Shanmughapriya S, Rajan S, Tomar D, Tahrir FG, Gupta MK, Knezevic T, Merabova N, Kontos CD, McClung JM, Klotman PE, Madesh M, Khalili K, Feldman AM. Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes. J Cell Physiol. 2019 Apr;234(4):4432-4444. doi: 10.1002/jcp.27232. Epub 2018 Sep 7. PubMed PMID: 30256393; PubMed Central PMCID: PMC6318060.
Myers VD, Tomar D, Madesh M, Wang J, Song J, Zhang XQ, Gupta MK, Tahrir FG, Gordon J, McClung JM, Kontos CD, Khalili K, Cheung JY, Feldman AM. Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis. J Cell Physiol. 2018 Sep;233(9):6319-6326. doi: 10.1002/jcp.26482. Epub 2018 Mar 30. PubMed PMID: 29323723; PubMed Central PMCID: PMC5993591.
Gupta MK, Kaminski R, Mullen B, Gordon J, Burdo TH, Cheung JY, Feldman AM, Madesh M, Khalili K. HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy. Sci Rep. 2017 Aug 17;7(1):8572. doi: 10.1038/s41598-017-08736-x. PubMed PMID: 28819214; PubMed Central PMCID: PMC5561171.
Knezevic T, Myers VD, Su F, Wang J, Song J, Zhang XQ, Gao E, Gao G, Muniswamy M, Gupta MK, Gordon J, Weiner KN, Rabinowitz J, Ramsey FV, Tilley DG, Khalili K, Cheung JY, Feldman AM. Adeno-associated Virus Serotype 9 – Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction. JACC Basic Transl Sci. 2016 Dec;1(7):647-656. doi: 10.1016/j.jacbts.2016.08.008. PubMed PMID: 28164169; PubMed Central PMCID: PMC5289821.
Gupta MK, Tahrir FG, Knezevic T, White MK, Gordon J, Cheung JY, Khalili K, Feldman AM. GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis. J Cell Biochem. 2016 Aug;117(8):1813-21. doi: 10.1002/jcb.25481. Epub 2016 Jan 21. PubMed PMID: 26729625; PubMed Central PMCID: PMC4909508.
Gupta MK, McLendon PM, Gulick J, James J, Khalili K, Robbins J. UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised Hearts. Circ Res. 2016 Jun 10;118(12):1894-905. doi: 10.1161/CIRCRESAHA.115.308268. Epub 2016 May 3. PubMed PMID: 27142163; PubMed Central PMCID: PMC4902739.
Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J. Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes. Circ Res. 2014 Sep 26;115(8):721-9. doi: 10.1161/CIRCRESAHA.115.304760. Epub 2014 Aug 5. PubMed PMID: 25097219; PubMed Central PMCID: PMC4180728.
Gupta MK, Gulick J, James J, Osinska H, Lorenz JN, Robbins J. Functional dissection of myosin binding protein C phosphorylation. J Mol Cell Cardiol. 2013 Nov;64:39-50. doi: 10.1016/j.yjmcc.2013.08.006. Epub 2013 Aug 31. PubMed PMID: 24001940; PubMed Central PMCID: PMC3847820.
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